<p>Vitamin B12, a member of the corrin family of compounds, is implicated in the formation of myelin, and along with Folate, is required for DNA synthesis . The most prominent source of B12 for humans is meat, while untreated fresh water can also be a source.Megaloblastic anaemia,characterised by elevated MCV, has been found to be due to B12 deficiency, a major cause being pernicious anaemia due to poor B12 uptake resulting in below normal serum levels. Other conditions related to low B12 levels include iron deficiency, normal near -term pregnancy, vegetarianism, partial gastrectomy, ileal damage, oral contraceptives, parasitic infestation, pancreatic insufficiency, treated epilepsy and advancing age. The correlation of serum B12 levels and megaloblastic anaemia, however, is not always clear- some patients with high MCV may have normal B12 levels, while some individuals with B12 deficiency may not have megaloblastic anaemia. Disorders like renal failure, liver disease and myeloproliferative disorder may have elevated vitamin B 12 levels.</p>
Sample Type - Blood
Reporting Time - Please Call Customer care
Prerequisites - No special preparation required
Price - ₹650/-
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